Synthèse des spirocyclopropanes via la cycloaddition dipolaire-1,3 du diazoacétate d’éthyle avec les arylidènes d’indan1’,3’-dione
Written by sctunisie no commentsSpiro-∆1pyrazolines 3a-e have been synthetized by 1,3-dipolar cycloaddition of some arylidenes of indan-1’,3’-dione 1a-e with ethyl diazoacetate 2. On heating under reflux, the spiroadducts 3a-e lose nitrogen molecule, thus being converted into spirocyclopropanes 4a-e. The proposed regio- and stereochemistry of cycloadducts 3a-e and 4a-e have been elucidated by 1H and 13C NMR.
N. Wannassi, M.M. Rammah, M.B.r Rammah, K. Ciamala
1,3-dipolar cycloaddition, ethyl diazoacetate, spiro-pyrazolines, spirocyclopropanes
Pages 117-125