JOURNAL of the Tunisian Chemical Society

serving the Research, the Education and the Industry

Synthèse d’isoxazolines et de spiro-isoxazolines par réaction de cycloaddtion dipolaire-1,3

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1,3-dipolar cycloaddition of arylnitriloxydes 1 on N-alkylmaleimides 2 realized in refluxing toluene leads to the corresponding isoxazolines. The synthesis of a new series of spiro-isoxazolines, by cycloaddition of arylnitriloxydes with les (E)-arylidène-N-arylsuccinimides 6 is reported. We also devoted a particular interest to the structural elucidation of such heterocyclic compounds.

N. Ben Hamadi, M. Msaddek

arylnitriloxides, 1,3-dipolar cycloaddition, isoxazoline, spiro-isoxazoline

Pages 115-120

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