JOURNAL of the Tunisian Chemical Society

serving the Research, the Education and the Industry

Structure of a new neo-clerodane diterpenoid from Ajuga pseudoiva leaves and its insect antifeedant and antibacterial activities

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From the leaves of the plant Ajuga pseudoiva a new neo-clerodane diterpenoid, Hativene D, has been isolated. Its structure was established by spectroscopic means. The antifeedant activity of this compound has been studied against Egyptian cotton leafworm Spodoptera littoralis (Boisd.) (Lepidoptera) by application of the leaf disk method. This substance exhibited an interesting activity even at 1 ppm. Structure-activity relationship is discussed. The antibacterial effect of this neo-clerodane has been also tested.

H. Ben Jannet, M.H. Oueslati, A. Chaari, M.T. Martin, A. Loukaci, M.J. Simmonds, Z. Mighri

Ajuga pseudoiva, Lamiacea, clerodane diterpenoid, Hativene D, anti-insect, antibacterial

Pages 1545-1549

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