Lateral functionalization of phosphonate quinolines
Written by sctunisie no commentsAn efficient metalation-functionalization of diethylmethylphosphonate quinolines, at low-temperature, with suitable electrophiles in the presence of n-BuLi in THF, is described herein. It constitutes a general method for the synthesis of halogenophosphonoquinolines and vinylquinolines.
N. Jelaiel, T. Saïed, M.L. Efrit
methylphosphonate, quinoline, halogenophosphonoquinoline, vinylquinoline
Pages 121-126