Synthèse de nouveaux amino dibenzohétéroazépines carbonitriles à partir de 2,3-dicyanocyclohexanoneWritten by sctunisie no comments
New amino dibenzoheteroazepine carbonitriles have been synthesized by condensation of 1,5,5-trimethyl-3-oxocyclohexane-1,2-dicarbonitrile, an isophorone derivative, with the o-phenylenediamine and its analogs. Several conditions have been used to optimize the yields. The activation of the reaction by irradiation microwaves proved to be very efficient. It led to shorter times of the reaction and to rate enhancements. Moreover, the purity of the products was increased.
N. Rachiqi, S. Fkih-Tetouani, A. El Louzi