Synthèse de nouveaux amino dibenzohétéroazépines carbonitriles à partir de 2,3-dicyanocyclohexanone
Written by sctunisie no commentsNew amino dibenzoheteroazepine carbonitriles have been synthesized by condensation of 1,5,5-trimethyl-3-oxocyclohexane-1,2-dicarbonitrile, an isophorone derivative, with the o-phenylenediamine and its analogs. Several conditions have been used to optimize the yields. The activation of the reaction by irradiation microwaves proved to be very efficient. It led to shorter times of the reaction and to rate enhancements. Moreover, the purity of the products was increased.
N. Rachiqi, S. Fkih-Tetouani, A. El Louzi
Pages 1433-1437
