JOURNAL of the Tunisian Chemical Society

serving the Research, the Education and the Industry

Synthèse et analyse conformationnelle par modélisation moléculaire des 1,N-bis-[4-phényl-1,5-benzodiaz.pin-2-oxo-1-yl] alcanes

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A number of 1,n-bis-(4-phenyl-1,5-benzodiazepin-2-oxo-1-yl(alcanes have been prepared by reaction between 4-phenyl-l,5-benzodiazepin-2-one and dihalogenoalcanes X-(CH2)n-X under phase transfert catalysis conditions. Also, we have study the conformational analysis by molecular modelisation of 1,n-bis-(4-phenyl-1,5-benzodiazepin-2-oxo-1yl-)alcanes.

R. Zniber, A. J El Hajjl, R. Achour, M.Z. Cherkaoui, A. Moussaif, M. El Ghoul, D. Guillon

benzodiazepin, conformational analysis, molecular modelisation, alkan dihalogenure

Pages 1223-1232

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