Preparation of chiral trichloromethyl alcohols in one step and their corresponding ketones
Written by sctunisie no commentsWe have prepared a serie of 18 chiral trichloromethylalcohols in one step by the reaction of trichloroacetic acid with the corresponding aldehyde using nitrobenzene as catalyst in dimethylsulfoxyde at 20°C.We have prepared the new ketones corresponding to the alcohols listed above using barium manganate as oxidant in dichloromethane.
I. Cheraief, T. Homri, B. Ben Hassine
trichloromethyl alcohols, trichloromethyl ketones, trichloroacetic acid, nitrobenzene
Pages 517-528
