JOURNAL of the Tunisian Chemical Society

serving the Research, the Education and the Industry

Action of amines and hydrazines derivatives on the N-(3-carbethoxy-2-trienyl) iminoethers: Synthesis of thieno [2-3-d] pyrimidin-4(3H)-ones

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N-(3-carbethoxy-2-thienyl) iminoethers 2, obtained from 2-amino-3-carbethoxythiophenes 1, react with primary amines and hydrazines derivatives to give thieno [2,3-d] pyrimidin-4(3H)-ones 3 and 4. From a mechanistic view point, the reaction proceeds by the intermediary amidines 3' which were isolated.

K. Dridi, M.L. El Efrit, H. Zantour

Pages 387-392

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