Reaction of Grignard reagents and LDA on N-2-cyano-2-methylvinyl and N-2-cyanophenyl iminoesters
Written by sctunisie no commentsReaction of the LDA and the Grignard reagents on the aliphatic N-2-cyano-2-methylvinyl and N-2-cyanophenylimidates provides aminopyridines and aminoquinolines respectively. In the absence of mobile hydrogen in a position with respect to the imidic carbon, the treatment of N-2-cyanophenyl-ethyl-benzimidate with organomagnesiums produces quinazolines.
M. Kamoun, B. Hajjem, H. Zantour, B. Baccar
Pages 883-889
