JOURNAL of the Tunisian Chemical Society

serving the Research, the Education and the Industry

Reaction of Grignard reagents and LDA on N-2-cyano-2-methylvinyl and N-2-cyanophenyl iminoesters

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Reaction of the LDA and the Grignard reagents on the aliphatic N-2-cyano-2-methylvinyl and N-2-cyanophenylimidates provides aminopyridines and aminoquinolines respectively. In the absence of mobile hydrogen in a position with respect to the imidic carbon, the treatment of N-2-cyanophenyl-ethyl-benzimidate with organomagnesiums produces quinazolines.

M. Kamoun, B. Hajjem, H. Zantour, B. Baccar

Pages 883-889

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