JOURNAL of the Tunisian Chemical Society

serving the Research, the Education and the Industry

Isolation of ergosterol peroxide from cyasterone from Ajuga iva leaves hemisynthesis of few structural analogous of cyasterone and study of their antibacterial activities

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Ergosterol peroxide and cyasterone have been isolated from the plant Ajuga iva. Their structural elucidation have been established by spectroscopic methods. We remind that ergosterol peroxide has been identified for the first time in the Ajuga genus. Seven structural analogous have been hemisynthezised from cyasterone, three of them are new. The study of the antibacterial activity of these structural analogous has allowed us to get an idea about sites taking part in this activity.

H. Ben Jannet, A. Chaarl, A. Bakhrouf, M. T. Martin, Z. Mighri

Ajuga iva, Labiatae, steroid, phytoecdysteroid, hemisynthesis, structural analogous, antibacterial activity

Pages 503-515

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