Acid catalysed addition reaction of Girard T reagent on cyclohexanone
Written by sctunisie no commentsAddition of Girard T reagent on cyclohaxanone in acidic medium is an equilibrinne reaction having a constant K which is equal to the ratio of formation constant (kf) over decomposition constant of the product (kd). Measuring and analysing kinetical constants allow to point out the occurrence of an acid catalysis for that reaction in water at 25.0°C in chlorhydrate, acetate, formiate and chloroacetate buffer solutions. Bronsted constants are also calculated for the formation (α = 0.25) and decomposition of the product (α = 0.20), and equilibrium constant is found to be equal to K = kf / kd = 114 ± 3.
L. Loubaki, T. Silou
Pages 23-27
