Action du 1,4-diazabicyclo [2.2.2] octane et de KCN sur les nitriles α,β-insaturés α-bromomethylés. Synthèse d'une famille de (E,Z)-2-alkyl-3-méthylbutènedinitriles
Written by sctunisie no commentsAllylic bromides 2-(E, Z) undergo smooth nucleophilic displacement with 1,4-diazabicyclo [2.2.2] octane (DABCO) and KCN in aqueous THF under mild conditions, to afford the corresponding 2-alkyl-3- methylbutenedinitriles 3(E, Z) with improved yields.
R. Ouled Saad, H. Amri
Pages 239 - 243
