JOURNAL of the Tunisian Chemical Society

serving the Research, the Education and the Industry

Approche mécanistique de l’hydrolyse acide des N-acyl-2,2-diméthylaziridines

Written by sctunisie no comments

The N-acyl-2,2-dimethylaziridines 1 are rearranged in presence of aqueous solutions of H2SO4 (3 et 23% wt) at room temperature for four days into a mixture of oxazolines 2, amidoalcohols 3 and N-methallylamides 4 with yields depending on the acidity of the media and the nature of acyl group of the aziridine 1. An mechanism has been advanced to explain the formation of these three products 2, 3 and 4.

M. Kamoun Mhiri, F. Aboumessaad, M.L. Efrit, N. Besbes

acid rearrangement, N-acylaziridine, isomerisation, mechanistic study

Pages: 127-132

Comments are closed.

Rss feed of the article's comments