Reaction of carboxylic esters and carbonylated derivatives on benzyl hydroximate dilithyated
Written by sctunisie no commentsAction of the two equivalent of the L.D.A. on ethyl benzylhydroximate leads to the corresponding dilithiohydroximate. The latter reacts with carboxylic esters and carbonated derivatives (aldehydes and ketones) to give after hydrolysis, the hydroxyled hydroximates which are treated with concentrated sulfuric acid, thus they are transformed accordingly into 1,2-oxazoles or 4,5-dihydro 1,2-oxazoles.
H. M’rabet, A. Bel Hadj Amor, B. Baccar
Pages 89-96
